Reglan
Cost: $40
IV Reglan is a prescription anti-nausea and pro-motility medication (metoclopramide) used for short-term relief of nausea, vomiting, and migraine-related symptoms. Given by IV, it starts working quickly and can be paired with hydration and other supportive therapies for comprehensive comfort—without opioids.
How IV Reglan Works
Reglan blocks dopamine (D₂) receptors in the brain’s chemoreceptor trigger zone to stop nausea signals, and it speeds stomach emptying (prokinetic effect) to reduce bloating and gastric stasis. The result is faster nausea relief and improved gut comfort. Many people feel improvement within minutes, with benefits often lasting several hours (varies by person).
Benefits At A Glance
- Fast relief of nausea and vomiting
- Helpful for migraines, especially when nausea is prominent
- Eases fullness/bloating by improving stomach motility
- Non-opioid option that can be combined with IV fluids and vitamins when appropriate
What IV Reglan Helps
- Acute nausea/vomiting (illness, medication or anesthesia-related, motion sensitivity)
- Migraine-associated nausea and headache discomfort
- Gastric stasis–type symptoms (functional “slow stomach” feelings such as early fullness/bloating)
Your clinician will determine if Reglan is appropriate for your specific symptoms.
Safety & Who Should Avoid It
IV Reglan is intended for short-term use and professional administration. It may not be appropriate if you have:
- Allergy to metoclopramide or similar medicines
- GI bleeding, obstruction, or perforation
- Pheochromocytoma (risk of hypertensive crisis)
- Seizure disorders, Parkinson’s disease, or history of tardive dyskinesia
- Pregnancy/breastfeeding: discuss risks/benefits with your clinician
Drug interactions: may increase sedation with alcohol, opioids, benzodiazepines, sleep aids; may raise risk of side effects with antipsychotics; use caution with SSRIs/MAOIs (serotonin-related effects). Always share a full medication list.
Possible Side Effects
Usually mild and temporary:
- Drowsiness, dizziness, headache
- Restlessness/akathisia (feeling fidgety or “antsy”)
- Diarrhea or GI cramping
Frequently Asked Questions
No—Reglan is a non-opioid anti-nausea/prokinetic medication.
Relief often begins in 15–30 minutes and may last 4–6 hours, depending on dose and individual response.
Yes. Reglan is commonly used for migraine-associated nausea and may also lessen headache intensity for some people.
Some people feel drowsy or restless. Plan light activities until you know how you respond.
If you cannot find an answer to your question, please reach out to us.
Call or Text (817) 646-8111
Email contact@utopiaiv.com
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